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Semaglutide is a synthetic glucagon-like peptide-1 (GLP-1) receptor agonist that has garnered significant attention in the field of endocrinology and metabolic research. Structurally similar to native GLP-1, semaglutide is designed with modifications that enhance its half-life and resistance to degradation by dipeptidyl peptidase-4 (DPP-4). This peptide binds to and activates the GLP-1 receptor, initiating a cascade of physiological responses that affect glucose homeostasis, appetite regulation, and cardiovascular function. Requires reconstitution before use.
Semaglutide
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Molecular Formula |
C187H291N45O59 |
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CAS Number |
910463-68-2 |
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Molar Mass |
4113.641 g/mol |
|
Amino Acid Sequence |
His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-COOH |
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Synonyms |
Semaglutide, Ozempic, Wegovy, NN9535, NN9934, GLP1, GLP-1 |
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Solubility |
Water-soluble |
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Organoleptic Profile |
White to off-white powder |
|
Composition |
Lyophilized powder – requires reconstitution |
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